Hi - probably the best place to start is to look at the example
higher-level analyses in the FEAT5 manual - these designs can all be
applied to TBSS output (apart from the fact that there's no
equivalent of "variance groups" in TBSS).
http://www.fmrib.ox.ac.uk/fsl/feat5/detail.html#higher
We generally just prefer explicit GLM group modelling with the
simplest possible set of EVs and asking specific questions with
contrasts - but as you can see in the manual, ANOVA designs are easy
too.
Cheers.
On 5 Oct 2006, at 10:17, Jeong Bum Seok wrote:
> Thank you for answer.
> Could I ask some question to understand your commnet?
> I have 3 group's data consting control, disease 1, disease1 with
> disease 2
> (combined group). I'd like to explore which tract is or are different
> among ds 1, combined group, and control. Hypothesis is that
> combined group
> may be most severe form and may be have most decreased FA value. So
> I'd
> like to use Glm function in TBSS.
> 1) You mean I can perform ANOVA with contrast (like fMR analysis)?
> 2) Can I perform posthoc analysis (ANOVA) like SPSS?
> Which contrast would be needed for posthoc?
> 3) Could you explain why you try to discourage people from ANOVA?
> 4) In my case, is there any other method rather than ANOVA?
>
> Thank you
>
> -----------------
> Hi,
>
> On 4 Oct 2006, at 14:14, Jeong Bum Seok wrote:
>
>> I'm beginer of FSL.
>> I've 2 questions.
>>
>> 1) I'd like to compare FAs of 3 independent group in TBSS.
>> Is it (ANOVA) possible?
>
> This simply relates to what model you test at the end, so yes is
> independent of the TBSS pre-stats processing - you can run any
> sensible model (though of course we always try to discourage people
> from using ANOVA in general ;-)
>
>> 2) Can I use own template that derived from my subjects rather than
>> MNI
>> template in TBSS? Please let me know which command line have to be
>> changed.
>
> This is pretty much what TBSS does - the MNI standard is simply there
> to set the final coordinate system with an affine transform, not as a
> registration target. Please read the TBSS manual/paper for more
> detail on this.
>
> Cheers, Steve.
>
>>
>> Thanks to advance
>
>
> ----------------------------------------------------------------------
> --
> ---
> Stephen M. Smith, Professor of Biomedical Engineering
> Associate Director, Oxford University FMRIB Centre
>
> FMRIB, JR Hospital, Headington, Oxford OX3 9DU, UK
> +44 (0) 1865 222726 (fax 222717)
> [log in to unmask] http://www.fmrib.ox.ac.uk/~steve
> ----------------------------------------------------------------------
> --
------------------------------------------------------------------------
---
Stephen M. Smith, Professor of Biomedical Engineering
Associate Director, Oxford University FMRIB Centre
FMRIB, JR Hospital, Headington, Oxford OX3 9DU, UK
+44 (0) 1865 222726 (fax 222717)
[log in to unmask] http://www.fmrib.ox.ac.uk/~steve
------------------------------------------------------------------------
---
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