Imperial College London
Faculty of Medicine
Division of Primary Care and Population Health Sciences
Statistical Analysis of Genetic Association Studies
28 - 29 September 2006
This is an intermediate level course aimed at researchers who already have a grasp of statistical methods (e.g. hypothesis testing, correlation, using regression models), and some familiarity with genetics data (e.g. terminology such as polymorphism, haplotype, SNP). An introduction to population genetics and linkage disequilibrium will be provided.
There will be exercises using the statistical package R: a brief refresher will be provided, but participants not currently familiar with R are strongly encouraged to download it (it's free and easy to install; see www.r-project.org) and to work through some of the examples in the "Introduction to R" document, available under "Manuals" on the above web page.
Summary of course content:
* Population genetics of LD
* Statistical measures of association
* Inferring haplotypes from genotypes
* Tagging and the Hap Map
* Population-based candidate-gene studies
* Genome-wide scans
* Population-based fine-scale mapping
* Family-based association studies
* Accounting for population substructure
Course Instructors:
Professor David Balding, Dr Maria De Iorio, & Dr Lachlan Coin, Imperial College, and Dr Andrew Morris, Wellcome Trust Centre for Human Genetics, Oxford.
Course Organiser: Professor David Balding
Course Fee (inc. lunch): £400 (industry) £300 (academic, inc non-profit organisations) £200 (Imperial Staff and full- time students)
Further details from: Wolfson Conference Centre
Imperial College School of Medicine
Hammersmith Hospital
Du Cane Road, London W12 0NN
Tel: +44 (0)20 8383 3117/3227/3245
Email: [log in to unmask]
Web: www.imperial.ac.uk/medicine/about/resources/wcc/default.html
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