We compared both equations with Cr-EDTA GFR measurements in patients with
diabetes and found that they had similar biases when expressed in the same
units.
Best wishes,
Brian Shine
> I know the MDRD equation (modified or not) has not been validated for use
> in chemotherapy. However in reality what are the Oncology teams using? I
> notice a recent trial uses Cockcroft and Gault. Has anyone details of a
> comparison? Is it possible that both have limitations and are equally
> imprecise?
> Finally since we have now modified the MDRD equation to allow for
> differences in the creatinine assay, why has the same criteria not been
> applied to the Cockcroft and Gault formula?
> Looking forward to the replies !!
> Helen
> ------------------------------------------------------------------------------------------
>
> Dr Helen Grimes, Dept Clinical Biochemistry, University College Hospital,
> Galway, Ireland
>
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