Apart from rifampicine [1,2] and the quinolones [3-5], which other molecules
can cause false positive immunoassay results for urine opiates?
Many thanks in advance,
Dr Joseph Watine
Laboratoire de Biologie Polyvalente
Centre Hospitalier Général
Rodez, France
1) de Paula M, Saiz LC, Gonzalez-Revalderia J, Pascual T, Alberola C,
Miravalles E. Rifampicin causes false-positive immunoassay results for urine
opiates. Clin Chem Lab Med 1998 Apr;36(4):241-3.
2) Herrera Trevilla P, Ortiz Jimenez E, Tena T, Lora Tamayo C. Presence of
rifampicin in urine causes cross-reactivity with opiates using the KIMS
method. J Anal Toxicol 1995 May-Jun;19(3):200.
3) Baden LR, Horowitz G, Jacoby H, Eliopoulos GM. Quinolones and
false-positive urine screening for opiates by immunoassay technology. JAMA
2001 Dec 26;286(24):3115-9.
4) Zacher JL, Givone DM. False-positive urine opiate screening associated
with fluoroquinolone use. Ann Pharmacother 2004 Sep;38(9):1525-8. Epub 2004
Jul 13.
5) Meatherall R, Dai J. False-positive EMIT II opiates from ofloxacin. Ther
Drug Monit 1997 Feb;19(1):98-9.
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