I had cause to visit my GP this morning and apropos of something we discussed
eGFR. In my humble but admittedly limited experience eGFR is almost as good as
a random number generator. My GP told me that in her experience she always
repeats the measurement if the first eGFR calculation has been made on a
creatinine from an overnight fasted samples. Use of a sample taken later in the
day after fluid intake almost invariably results in a significant improvement
in the eGFR. I tentatively propose the term TeGFR for this new measurement.
Two important questions arise from this observation. Firstly except for those
analytes clearly altered by meals is there a risk in using fasting samples?
Secondly when should samples for eGFR be taken, if ever?
Over to you.
Happy Christmas to you all
Mike Addison
Locum (but not for too much longer) Consultant Biochemist
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