Last year, we had the same problems and did some experiments:
- First, in a limited amount of samples we found that glucose results were
valid despite clotting (clotted tubes vs non-clotted tubes from the same
patient)
- Second, because we suspected insufficient mixing being the cause, we did
some experiments with extensively mixed tubes and found that even then
clotting occurs. So the BD comments that clotting does not occur when tubes
are mixed appropriately is bullshit
- A new batch of tubes (sorry, I don't know these batchnumbers anymore),
apparently with appropriate concentration of fluoride oxalate, eliminated
the problem
In my opinion BD should improve their quality control procedures and
manufacture products of stable and appropriate quality and not hide
themselves behind the argument that improper mixing is causing these
problems
Hope these experiences will help
Andries
Dr. A. J. Bakker, Klinisch chemicus,
St. Klinisch Chemisch Laboratorium,
Postbus 850,
8901 BR LEEUWARDEN.
Tel.: 058-2888444
Fax: 058-2882227
E-mail: [log in to unmask]
> -----Oorspronkelijk bericht-----
> Van: Clinical biochemistry discussion list
> [SMTP:[log in to unmask]] Namens Tilbrook Louise (RQ8) Mid
> Essex Hospital
> Verzonden: donderdag 2 maart 2006 15:43
> Aan: [log in to unmask]
> Onderwerp: BD Fluoride oxalate vacutainers
>
> Over the past week or so we have experienced problems with a number of
> fluoride oxalate specimens clotting. We use BD 2mL vacutainers (FX 5mg
> 4mg) and our current batch details are: REF 367934 LOT5181416
> EXP 2006-10.
>
> Our assumption is that if the specimens are clotted then they are
> unsuitable for glucose analysis.
>
> If any other mailbase users have experienced similar problems recently I
> would be very interested to know the details.
> Many thanks
>
> Louise Tilbrook
>
> Louise Tilbrook
> Principal Clinical Scientist
> Department of Clinical Biochemistry
> Broomfield Hospital
> Chelmsford
> Essex
> CM1 7ET
>
> Phone:01245 514013
> Fax: 01245 514077
> [log in to unmask]
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