JiscMail Logo
Email discussion lists for the UK Education and Research communities

Help for AGEING Archives


AGEING Archives

AGEING Archives


AGEING@JISCMAIL.AC.UK


View:

Message:

[

First

|

Previous

|

Next

|

Last

]

By Topic:

[

First

|

Previous

|

Next

|

Last

]

By Author:

[

First

|

Previous

|

Next

|

Last

]

Font:

Proportional Font

LISTSERV Archives

LISTSERV Archives

AGEING Home

AGEING Home

AGEING  September 2005

AGEING September 2005

Options

Subscribe or Unsubscribe

Subscribe or Unsubscribe

Log In

Log In

Get Password

Get Password

Subject:

Critical Information About Possible Side Effect of Bisphosphonates

From:

"Kathrynne Holden, MS, RD" <[log in to unmask]>

Reply-To:

Kathrynne Holden, MS, RD

Date:

Wed, 28 Sep 2005 10:08:41 -0500

Content-Type:

text/plain

Parts/Attachments:

Parts/Attachments

text/plain (95 lines)

Colleagues, the following is FYI and does not necessarily reflect my own
opinion. I have no further knowledge of the topic. If you do not wish to
receive these posts, set your email filter to filter out any messages
coming from   @[log in to unmask]    and the program will remove
anything coming from me.
---------------------------------------------------------
Keywords: OSTEOPOROSIS, OSTEONECROSIS, JAW, ENDODONTICS, BISPHOSPHONATES
Source: Edelman PR, Chicago 	  	
Released: Wed 28-Sep-2005, 07:00 ET
http://www.newswise.com/articles/view/514901/?sc=dwhp

Critical Information for Patients About Possible Side Effect of 
Bisphosphonates

Newswise — An article titled, “Bisphosphonate-associated Osteonecrosis 
of the Jaws and Endodontic Treatment: Two Case Reports,” in the October 
issue of the Journal of Endodontics (JOE), a publication of the American 
Association of Endodontists (AAE), suggests patients using 
bisphosphonates as part of their cancer treatment and for debilitating 
bone diseases, such as osteoporosis and Paget’s disease, may be at risk 
of experiencing a painful, disfiguring condition known as osteonecrosis 
of the jaw, a disease that leads to the breakdown of the bone. The word 
osteonecrosis literally means “death of bone” (osteo = bone, necrosis = 
death).

Initial symptoms include burning, tingling or localized pain in the jaw, 
and may lead to more serious complications, such as infections and 
jawbone degeneration. Patients who think they may be experiencing 
symptoms of osteonecrosis of the jaw should seek counsel from their 
general physicians and oncologists, and inform their dentists, 
endodontists and other dental professionals that they are undergoing 
treatment with bisphophonates.

The latest generation of bisphosphonates includes: alendronate 
(Fosamax®); pamidronate (Aredia®); and zoledronate (Zometa®). 
Bisphosphonates help strengthen bone and prevent fractures in the hip, 
spine and other skeletal regions by inhibiting bone loss.

The article indicates that at the same time bisphosphonates support the 
buildup of bone in areas weakened by disease or as a side effect of 
treatment, some patients taking bisphosphonates may experience the 
opposite effect in the lower and upper jawbones. “Considering the large 
number of patients around the world using bisphosphonates for prevention 
or treatment of osteoporosis, dentists may be dealing with a significant 
potential complication,” write the authors.

Written by Aaron P. Sarathy, D.M.D., Sidney L. Bourgeois, Jr., D.D.S. 
and Gary G. Goodell, D.D.S., M.S., M.A., the article suggests that 
problems in some patients using bisphosphonates may be triggered by a 
dental procedure, such as a tooth extraction, or could occur spontaneously.

To prevent complications, the article suggests that those who take 
bisphosphonates seek counsel from their medical and dental providers 
before any elective dental procedures, and that any non-elective dental 
work – especially extractions, which, the article notes appear to 
“precipitate the majority of this condition” – be done before starting 
bisphosphonate therapy. When dental work is required after starting 
bisphosphonate therapy, patients, physicians and general dentists should 
consult with appropriate dental specialists, including endodontists, 
because non-surgical root canal treatment may be a safer alternative to 
extraction.

“Bisphosphonates are important drugs that help manage the side effects 
of cancer treatments, as well as bone loss in people who have 
osteoporosis,” says JOE Editor Kenneth M. Hargreaves, D.D.S., Ph.D.. 
“But, as this article indicates, both healthcare professionals and 
patients should be aware of the risks so together they can ensure 
optimal dental treatment.”

American Association of Endodontists
The American Association of Endodontists, headquartered in Chicago, 
represents more than 6,600 members worldwide, including approximately 95 
percent of all eligible endodontists in the United States. The 
Association, founded in 1943, is dedicated to excellence in the art and 
science of endodontics and to the highest standard of patient care. The 
Association inspires its members to pursue professional advancement and 
personal fulfillment through education, research, advocacy, leadership, 
communication and service. For more information, visit the AAE Web site 
at http://www.aae.org.

Complete article and abstract available to the media by contacting 
Krista Sabia or Craig Samuels at Edelman.
-- 
Kathrynne Holden, MS, RD < [log in to unmask] >
"Ask the Parkinson Dietitian"  http://www.parkinson.org/
"Eat well, stay well with Parkinson's disease"
"Parkinson's disease: Guidelines for Medical Nutrition Therapy"
http://www.nutritionucanlivewith.com/

----------------------------------------------------------------
This message was sent through the Ageing in Europe
mailing list.
Please visit the homepage of the ESA Research Network
on Ageing in Europe at http://www.ageing-in-europe.de
----------------------------------------------------------------

Top of Message | Previous Page | Permalink

JiscMail Tools


RSS Feeds and Sharing


Advanced Options


Archives

November 2018
October 2018
September 2018
August 2018
July 2018
June 2018
May 2018
April 2018
March 2018
February 2018
January 2018
December 2017
November 2017
October 2017
September 2017
August 2017
July 2017
June 2017
May 2017
April 2017
March 2017
February 2017
January 2017
December 2016
November 2016
October 2016
September 2016
August 2016
July 2016
June 2016
May 2016
April 2016
March 2016
February 2016
January 2016
December 2015
November 2015
October 2015
September 2015
August 2015
July 2015
June 2015
May 2015
April 2015
March 2015
February 2015
January 2015
December 2014
November 2014
October 2014
September 2014
August 2014
July 2014
June 2014
May 2014
April 2014
March 2014
February 2014
January 2014
December 2013
November 2013
October 2013
September 2013
August 2013
July 2013
June 2013
May 2013
April 2013
March 2013
February 2013
January 2013
December 2012
November 2012
October 2012
September 2012
August 2012
July 2012
June 2012
May 2012
April 2012
March 2012
February 2012
January 2012
December 2011
November 2011
October 2011
September 2011
August 2011
July 2011
June 2011
May 2011
April 2011
March 2011
February 2011
January 2011
December 2010
November 2010
October 2010
September 2010
August 2010
July 2010
June 2010
May 2010
April 2010
March 2010
February 2010
January 2010
December 2009
November 2009
October 2009
September 2009
August 2009
June 2009
May 2009
April 2009
March 2009
February 2009
January 2009
December 2008
November 2008
October 2008
September 2008
July 2008
June 2008
May 2008
April 2008
March 2008
February 2008
January 2008
December 2007
November 2007
October 2007
September 2007
August 2007
July 2007
June 2007
May 2007
April 2007
March 2007
February 2007
January 2007
December 2006
November 2006
September 2006
August 2006
June 2006
May 2006
April 2006
March 2006
February 2006
January 2006
December 2005
November 2005
October 2005
September 2005
August 2005
July 2005
June 2005
May 2005
April 2005
March 2005
February 2005
January 2005
December 2004
November 2004
October 2004
September 2004
August 2004
July 2004
June 2004
May 2004
April 2004
March 2004
February 2004
January 2004
December 2003
November 2003
October 2003
September 2003
August 2003
July 2003
June 2003
May 2003
April 2003
March 2003
February 2003
January 2003
December 2002
November 2002
October 2002
September 2002
August 2002
July 2002
June 2002
May 2002
April 2002
March 2002
February 2002
January 2002
December 2001
November 2001
October 2001


JiscMail is a Jisc service.

View our service policies at https://www.jiscmail.ac.uk/policyandsecurity/ and Jisc's privacy policy at https://www.jisc.ac.uk/website/privacy-notice

Secured by F-Secure Anti-Virus CataList Email List Search Powered by the LISTSERV Email List Manager