Much appreciated - we noticed some difference when changing from Vitros
BCG to Abbott C8000 BCP method but less than 5 g/L for GP/outpatients.
What do others do over reporting adjusted calcium in the newborn and
infants who "normally" have lower albumin ranges ?
Paul
Dr Paul Eldridge
Clinical Biochemist
University Hospital Lewisham
London SE13 6LH
UK
Phone: (44) 020 8333 3255
Fax: (44) 020 8690 8891
>>> Brian Payne <[log in to unmask]> 22/09/04 10:38:26 >>>
With modern methods BCG seems to measure a constant amount of globulin
over a very wide range of albumin conentrations, giving values that
average 5 g/L greater than BCP (Ann Clin Biochem 1988; 25: 417). So,for
example, the BCG equation
Adjusted calcium = measured calcium + (40 - BCG albumin)*0.025
becomes
Adjusted calcium = measured calcium + (35 - BCP albumin)*0.025
If possible, it is best to derive your own equation from your
laboratory database (see Ann Clin Biochem 1996; 33: 55-58).
Brian Payne
IAN WATSON wrote:
>Should one change the calculation for adjusted calcium from that used
with BCG when using BCP? Particularly as there are more 'low end'
albumins with the latter is there a risk of an excess 'mild adjusted
hypercalcaemia'?
>
>Ian Watson
>Univ Hosp Aintree
>
>
>
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