Dear Brad,
>Has anyone segmented the standard brain into Brodmann's areas or
>identified the locations of
>cortices such as motor, premotor, sma, auditory, etc.???
Tricky question! To do it right requires generating probabilistic maps
according to some criterion. Several groups have done these for a variety
of regions and using a variety of crieteria, so I guess the answer to your
questions is "yes." See papers by Zilles' group, Penhune & Rademacher for
auditory cortex, Westbury & others for planum temporale, Tomaiuolo for pars
opercularis, etc. The problem is that "standard space" is defined by the
mean of 152 brains so there is no clear cut segmentation -- there is only a
probabilistic distribution that any given coordinate falls into a
particular area. However, there is no comprehensive probabilistic map of
the entire cortex,a s far as I know. I think the MNI has a web page about
these probabilistic maps -- you might check there.
If you meant, "Have the regions of the Colin brain been segmented?", then
the answer is again yes. This is the high res, high quality single subject
brain that many packages use as a "canonical" template (eg SPM,
MRIcro). See Tzourio-Mazoyer et al. (2002) Neuroimage.
Jan;15(1):273-89. They provided a toolbox add-in to SPM and I think the
scheme comes with the MRIcro package, too.
Having said this, there really is no easy, fool-proof method for
identifying brain regions in standard space. Your best bet is always to
superimpose them on your subject(s)' anatomical scan and manually identify
the regions using something like the Duvernoy atlas as a reference.
Hope this helps.
Joe
--------------------
Joseph T. Devlin, Ph. D.
FMRIB Centre, Dept. of Clinical Neurology
University of Oxford
John Radcliffe Hospital
Headley Way, Headington
Oxford OX3 9DU
Phone: 01865 222 494
Email: [log in to unmask]
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