Dear Andrew,
Greetings from coastal Suffolk in England. There seems to be lot of
literasture on the analysis of cluster randomised trials. Although I could
not find a direct answer to your question, I thought you might find the
following papers of some interest.
Chuang JH, Hripcsak G, Jenders RA. Considering clustering: a methodological
review of clinical decision support system studies. Proc AMIA Symp
2000;:146-50. Full text draft available on line @
http://www.cpmc.columbia.edu/homepages/hripcsa/Publication/2000_AMIA_Chuang_cluster.doc
Simpson JM, Klar N, Donnor A. Accounting for cluster randomization: a review
of primary prevention trials, 1990 through 1993. Am J Public Health 1995
Oct;85(10):1378-83
Unit of analyses errors in cluster randomised trials to evaluate the
effectiveness clinical guidelines dissemination and implementation
strategies
Graeme MacLennan, Ruth Thomas, Jeremy Grimshaw and Craig Ramsay
BMC Meeting Abstracts: 9th International Cochrane Colloquium 2001, 1:op054
http://www.biomedcentral.com/abstracts/cochrane/1/op054/
Ukoumunne OC, Gulliford MC, Chinn S, Sterne JAC, Burney PGJ. Methods for
evaluating area-wide and organisation-based interventions in health and
health care. Health Technol Assess 1999;3(5).
Maclennan G, Ramsay C, Grimshaw JM, Campbell MK. Analysis did not account
for cluster randomisation. BMJ 2000 Dec 9;321(7274):1473
Full free text @ http://bmj.com/cgi/content/full/321/7274/1473
Mollison J, Simpson JA, Campbell MK, Grimshaw JM. Comparison of analytical
methods for cluster randomised trials: an example from a primary care
setting. J Epidemiol Biostat 2000;5(6):339-48
Elbourne DR, Campbell MK. Extending the CONSORT statement to cluster
randomized trials: for discussion. Stat Med 2001 Feb 15;20(3):489-96
Hope this is of some help,
Cheers & regards,
Badri
Dr.P.Badrinath M.D,M.Phil,(Epid)PhD(Cantab)DFPHM,MPH(Distinc)
Specialist Registrar in PHM & Honorary Clinical Lecturer,
Suffolk Public Health Network & University of Cambridge,
PO Box 170, St.Clement's Hospital,
Ipswich IP1 4LA, UK. http://myprofile.cos.com/badrishanthi
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