An established measure is the Likelihood Ratio (LR). You may use the LR+ and LR-
for each cutoff point, or you can use multilevel likelihood ratio which is the
LR for each outcome of the test. The latter is not so much used.
Centor RM. Estimating confidence intervals of likelihood ratios. Med Decis
Making 1992;12:229-33.
Regards
Roland Andersson, MD PhD
Department of Surgery
County Hospital Ryhov
S-551 85 Jönköping
SWEDEN
e-mail: [log in to unmask]
phone: +46-36-321344
fax: +46-36-321321
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David manton wtote:
I am familiar with traditional diagnostic indices
(e.g. sensitivity and specificity) for quantifying
the efficacy of a particular test when the diagnosis
is based around TWO categories/groups (e.g. benign
versus malignant tumours).
My question is, are there any similar, established
methods/indices for quantifying diagnostic efficacy
when there are MULTIPLE categories/groups (e.g.
malignant tumours, totally benign tumours and
benign tumours regarded clinically as having an
increased chance of progressing into malignant disease
because of co-existant pathology)?
David Manton, Ph.D. (Medical Physics)
YCR Centre for MR Investigations,
Hull Royal Infirmary, Anlaby Road, Hull, UK. HU3 2JZ
mailto:[log in to unmask]
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