Research Associate/Assistant 'Medical Statistician - (Systematic Reviews & Meta-analysis)' - Ref: 1732436
UCL Department / Division: MRC Clinical Trials Unit at UCL
Location of position: London
Hours: Full Time
Salary (inclusive of London allowance): Grade 6B £30,316 - £31,967 per annum - Grade 7 £34,635 - £41,864 per annum
Duties and Responsibilities:
The MRC Clinical Trials Unit is seeking a motivated individual to play a key role in an exciting 5-year programme of activity funded by a Prostate Cancer UK Innovation Award and the UK Medical Research Council (MRC), with worldwide collaborators. The programme has been developed to speed up the evaluation of treatments for metastatic (M1) prostate cancer. Ultimately, this will help give men faster access to life-saving treatments, by:
* producing systematic reviews and network meta-analyses of aggregate and individual participant data (IPD) from randomised controlled trials (RCTs) of current therapies;
* identifying and validating early outcomes for survival to help speed up future trials;
* developing a repository of RCT data as a unique resource for the global prostate cancer community.
* Liaison with the Repository manager and trial investigators/statisticians worldwide to ensure safe and secure transfer of trial IPD; developing data management plans, programmes and ensuring consistency.
* Making a major contribution to the design and development of the Repository, and take primary responsibility for the day-to-day maintenance.
* Developing statistical analysis plans and working procedures, and undertaking statistical analysis and meta-analyses of multiple trials.
* Preparing and discussing of data and analysis reports.
* Contributing to the production of abstracts and presentations for conferences, and papers for submission to medical journals.
* Presenting results at Collaborators meetings and at conferences.
* Contributing to the development and implementation of novel methods for systematic review design, conduct and analysis and their implementation in real-world settings.
* Developing knowledge of the biology and epidemiology of prostate cancer, and of relevant statistical and methodological techniques.
The successful candidate will have an enthusiastic approach, excellent communication skills, and proven ability to prioritise and work to deadlines. S/he should have a good understanding of statistical concepts and of randomised controlled trials principles, as well as familiarity with one or more statistical packages, particularly in the context of data management. An understanding of systematic review principles and experience of using statistical methods in the analysis of individual participant data in a meta-analysis context are both desirable.
S/he will have practical experience of statistical methods in analysing trial data, and experience of working with multi-disciplinary teams and preparing/presenting reports.
S/he will have enthusiasm to manage a large repository of individual participant data and be able to communicate effectively and professionally with a wide range of stakeholders at all levels.
Knowledge of the biology and epidemiology of cancer is desirable.
Candidates may also be interested in three other roles currently being advertised:
Ref: 1732458 Medical Statistician (Clinical Trials) x2
Ref: 1732462: Medical Statistician (Clinical Trials)
Re: 1732464: Medical Statistician in Methodological Software
If you have any queries regarding the vacancy or the application process, please contact Carole Booth on ([log in to unmask]<mailto:[log in to unmask]>) or for an informal discussion regarding the post please call either David Fisher (Tel: +44 (0)207 670 4646) or Dr Jayne Tierney (Tel: + 44 (0)20 7670 4724).
For more information, please click HERE<https://atsv7.wcn.co.uk/search_engine/jobs.cgi?owner=5063744&ownertype=fair&jcode=1732436&vt_template=966&adminview=1>
Closing Date: 23 Jul 2018
Latest time for the submission of applications: 23:59
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