I'm afraid we are still working on a longitudinal version of vertex analysis.
You can't implement a paired t-test with the current FIRST tools.
However, you could save out the vertex coordinates using the --saveVertices
option and then use other statistical packages to implement a multivariate
Hope that helps.
All the best,
On 5 May 2012, at 05:49, Luke wrote:
> Dear FSL-Experts!
> I wonder if FIRST can be used for longitudinal studies ( in my case 2 groups (Placebo / Intervention) examined at two points (T1/T2)). The analysis of the subcortical volumes via fslstats already revealed the expected result. Now I would like add a vertex analysis to infer shape changes due to the on the effect of the intervention. Is there any issue of theoretical or practical kind that might argue against performing a vertex analysis in this situation? Any recommendations for the first_utils options in this situation?
> Best wishes and many thanks in advance,