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Subject:

iCASE PhD opportunity at the University of Warwick

From:

Geraint Parry <[log in to unmask]>

Reply-To:

Geraint Parry <[log in to unmask]>

Date:

Thu, 15 Mar 2018 09:45:12 +0000

Content-Type:

multipart/mixed

Parts/Attachments:

Parts/Attachments

text/plain (53 lines) , iCASE KWS advert.docx (53 lines)

PhD Opportunity: BBSRC – Industrial Cooperative Awards in Science & 
Technology (ICASE)

Application Deadline: 27th April 2018

Area of Research: New methodologies to enhance phenotypic variation in 
crops

Compared to animals, somatic cells of plants can be much more easily 
reprogrammed to regenerate whole new organs and, sometimes, entire 
individuals. This unique biological property has enabled plants to 
reproduce either sexually or asexually according to their habitat. The 
ability of plant cells to readily acquire a totipotent state has been 
attributed to their flexible epigenetic states. As a result, plant 
totipotency has been traditionally exploited by humans for the clonal 
propagation and genetic manipulation of economically important species. 
However, clonal plants are not always phenotypically identical to their 
parents, a phenomenon not well understood. Our recent data indicates 
that this form of phenotypic variation is linked to the accumulation of 
epigenetic modifications as a consequence of incomplete resetting of 
somatic imprints. The aim of this project is to use this knowledge and 
develop technologies to enhance phenotypic diversity in crop elite lines 
by the targeted manipulation of the genome.

The student will assess novel routes to enhance phenotypic diversity in 
model plants and elite crop varieties, primarily focusing on identifying 
the genetic and epigenetic changes created during cloning and developing 
tools to enhance plant performance through targeted genome manipulation.

The student will be mainly based in the department of Life Science at 
Warwick. S/He will spend up to 3 months at KWS and will undertake 
extensive training opportunities provided by the BBSRC funded Midlands 
Integrative Biosciences Training Partnership (MIBTP).

The candidate would be expected to have at least a 2:1 degree on Biology 
or a science related subject. The studentship covers the 4 year value of 
stipend, fees and incidental costs for home students. The studentship 
will start in October 2018. More information about MIBTP can be found 
at: https://warwick.ac.uk/fac/cross_fac/mibtp/.

For applications please apply via the online application form 
https://postgrad.warwick.ac.uk/SWIFT.web/skins/pgapp/login.aspx, 
selecting course code P-C1PB (Life Sciences PhD). In the finance section 
of the form please enter MIBTP and iCASE “Enhanced phenotypic 
variation”.

Enquires about the studentship should be directed to:

Dr. Jose Gutierrez-Marcos, School of Life Sciences, University of 
Warwick, Coventry, CV4 7AL. Tel: +44 (0)2476 575077. Email: 
[log in to unmask]

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