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Hi! The list I found - which is quite comprehensive is: Contraindications to fibrinolysis ABSOLUTE CONTRAINDICATION Active internal bleeding CVA within 6 months Cranial or spinal surgery within 2 months Cerebral or spinal tumor or arteriovenous malformation Severe bleeding diathesis (moderate, such as von Willebrand's, acceptable) BP >200/120 not amenable to emergency department therapy Allergy to fibrinolytic agent RELATIVE CONTRAINDICATION Cerebrovascular disease Gastrointestinal or urologic bleeding within 10 days Significant surgery or trauma within 10 days, including puncture of noncompressible vessels BP >180/110 Suspected left heart thrombus (such as mitral stenosis with atrial fibrillation) Suspected aortic dissection or pericarditis Subacute bacterial endocarditis Known coagulation defect (including severe liver dysfunction) Pregnancy (Category C) Active hemorrhagic ophthalmic disease Septic thrombophlebitis or occluded arteriovenous cannula at infected site Warfarin use (manufacturer's recommendation, no data) For tPA, age over 75 years, small infarctions, or MI onset >6 hours (no advantage over streptokinase) For streptokinase, streptococcal infection or streptokinase use within 1 year ----- Original Message ----- From: Jel Coward <[log in to unmask]> To: <[log in to unmask]> Sent: Sunday, September 05, 1999 3:22 PM Subject: Contraindications to thrombolysis in MI > Hi all > > I am after a definitive/semi-definitive list of contraindications to > thrombolysis in MI > > I have found several lists from different hospitals and have the > Clinical Resource and Audit Group's list from Drugs 1995 > > I need to put a list together for a lecture and had a prolonged and > interesting discussion about this today > > I would be interested in any lists that people use and any evidence that > there is for these > > I haven't done a more detailed search yet but will post results of this > if folk are interested - (cos I feel guilty about scrounging again) > > TIA > > Cheers all > -- > Jel Coward > > ..take a look at the Wilderness Emergency Medicine and Command Physician courses > > http://www.wildmedic.org > > [log in to unmask] > > 'There's no such thing as bad weather - just bad clothing" > Anon Norwegian > %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%