To: ACAD_AE_MED There is a lot of discussion about rapid sequence induction both in pre-hospital care and in the A&E department. Here is some evidence as to why we need to do it. Of course the next step is who should do it - simple answer the first person there who is appropriately trained person and can perform RSI safely. Matthew Authors Li J. Murphy-Lavoie H. Bugas C. Martinez J. Preston C. Institution Accident Room, Charity Hospital, New Orleans, LA, USA. Title Complications of emergency intubation with and without paralysis. Source American Journal of Emergency Medicine. 17(2):141-3, 1999 Mar. Abstract Expert and definitive airway management is fundamental to the practice of emergency medicine. In critically ill patients, rapid sedation and paralysis, also known as rapid-sequence intubation, is used to facilitate endotracheal intubation in order to minimize aspiration, airway trauma, and other complications of airway management. An alternative method of emergent endotracheal intubation, intubation minus paralysis, is performed without the use of neuromuscular blocking agents. The present study compared complications of these two techniques in the emergency setting. Sixty-seven intubations minus paralysis were prospectively compared with 166 rapid-sequence intubations. Complications were greater in number and severity in the nonparalyzed group and included aspiration (15%), airway trauma (28%), and death (3%). None of these difficulties were observed in the rapid- sequence group (P < .0001). These results show that rapid-sequence intubation when compared with intubation minus paralysis significantly reduces complications of emergency airway management and should be made available to emergency physicians trained in its use. Dr Matthew Cooke Senior Lecturer in Emergency Care Emergency Medicine Research Group Primary Care Unit, Univ of Warwick Tel 024 76 573005 Fax 0870 055 8087 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%