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MEDICAL RESEARCH COUNCIL BIOSTATISTICS UNIT - CAMBRIDGE 2 STATISTICIAN POSTS The MRC Biostatistics Unit has two positions available. Letter of application with 2 copies of full CV and names and addresses of 2 referees should be sent to: Dr. Linda Sharples, MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge, CB2 2SR as soon as possible, and not later than 16th July 1999. Both candidates will be appointed to MRC Band 4, salary range 15,500-28,900 GBP per annum depending on qualifications and experience. 1) MODELLING OF VARIABILITY IN EXPOSURE TO CHEMICALS IN FOODS The first post is an eighteen-month appointment for a statistician to play a major part in a challenging project to model variability and uncertainty in individuals' exposure to chemicals in foods. The project is sponsored by the Ministry of Agriculture, Fisheries and Food (MAFF). The project and the post will be based at the MRC Biostatistics Unit within the Institute for Public Health of the University of Cambridge. The work will entail combining disparate datasets of food consumption and concentrations of chemical contaminants in foods, and estimating within- and between-subject variability in food chemical exposure, accounting as much as possible for uncertainty and bias. It is planned to use generalised mixed linear models with Bayesian Markov Chain Monte Carlo estimation of parameters for this work. the work is supervised by Mr Stephen Duffy at the MRC Biostatistics Unit, and Dr Gill Price at the MRC Institute for Environment and Health. Liaison will be required throughout the project with government scientists at MAFF in London. A postgraduate qualification in statistics and some experience of computer programming are both necessary for this post. Experience of mixed or random effects models would be an advantage, as would the ability to communicate principles and details of the work with non-statisticians. Further details of the post may be obtained from either Stephen Duffy at the MRC Biostatistics Unit (tel. 01223-330397), or Gill Price at the MRC Institute for Environment & Health in Leicester (tel. 0116-2231629). Stephen W. Duffy, MRC Biostatistics Unit, Institute of Public Health, University Forvie Site, Robinson Way, Cambridge CB2 2SR Tel 01223 330397 Fax 01223 330388 email [log in to unmask] 2) METHODS ARISING FROM CARDIOTHORACIC APPLICATIONS The second post involves a broad range of activities arising from collaboration with Papworth Hospital NHS Trust. The post is funded by Papworth and is tenable for three years. The post would be suitable for those with a Masters degree or near completion of a PHD in statistics or medical statistics. The ability to work independently with quantitative methods and good communication skills are necessary. The successful candidate will spend 2-3 days per week working at Papworth undertaking applied and collaborative research as well as contributing to the teaching courses which are held there. The remainder of the time will be spent at the Biostatistics Unit where methodological work will be carried out. The post holder will take responsibility for one of the national clinical trails run from Papworth and will help to develop methods for analysing epidemiological data arising from the transplant cohorts. There is a great deal of potential in the post to develop skills in a wide range of methodological and applied areas. The post-holder will be directly responsible to Dr. Linda Sharples at the MRC Biostatistics Unit and will work closely with Ms. Noreen Caine, Director of R&D at Papworth. The post-holder will be required to: Research * Pursue personal research in the area of medical statistics * Undertake collaborative projects in transplantation and cardiothoracic medicine * Supervise the data collection and analysis of clinical trials * Publish high quality papers based on the above work * Present research at national and international meetings Teaching * Contribute to courses on research skills for clinical and allied professions * Assist in training clinical and allied professions in use of statistical software * Contribute to the supervision of Postgraduate students allied to the cardiothoracic applications programme if appropriate Other duties * Contribute to the provision of statistical consulting within Papworth Hospital * Help to develop research projects for funding applications in the region Dr. Linda Sharples MRC Biostatistics Unit Institute of Public Health Cambridge, CB2 2SR Tel: (0)1223 330389 FAX: (0)1223 330388 e-mail: [log in to unmask] %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%