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Many thanks to all of you who commented on my CK-MB Troponin I discrepancy problem. To answer some of your requests for further info the lady was euthyroid by TSH & fT4 (also on AxSYM !!). CK isoenzymes by electrophoresis, thanks to colleagues in Liverpool, showed 2.4% CK-MB which is at an "equivocal" level. They also kindly repeated the Troponin T which confirmed earlier troponin findings. On balance I think this is an example of over-estimation by the AxSYM CK-MB assay - a phenomenon which any assay seems capable of producing on occasions, though some more often than others. I am waiting for a reply from Abbott. This time TnI seems to have been most reliable. Geoff Lester %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%