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A GP told me that a patient had shown her a leaflet about an osteoporosis test sold by a local pharmacy. This is a urine test sold directly to patients, and costs about £20. I think it is a collagen cross-link metabolite assay. My question are: What is the positive predictive value for, say, fracture of the femur? What is the sensitivity and specificity? Is the £20 well spent? Comments, or answers to any of these questions, would be appreciated (especially from those of you without a commercial interest). Robin Marks \/ \/ \/ \/ \/ \/ \/ /\____/\____/\____/\____/\____/\____/\____ %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%