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A 78 year old lady was admitted in a drowsy state with a tender abdomen and DKA. She had been originally been treated elswhere and we were told her amylase was 1800. On admission to us she was still in DKA and had an amylase of 710U/L (Vitros 750 ref range 40 - 110). Her DKA was treated appropriately and succesfully and her amylase dropped over two days to 410U/L. On the third day the amylase started to rise, 528U/L and it was noticed that her parotid glands had become hard and swollen. We cannot decide if her high amylase levels were due to pancreatitis, DKA or could it be salivary? Does anyone know about or have the ability to differentiate between salivary and pancreatitic amylase? Paul Robinson Royal Berkshire Hospital Reading %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%