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Thanks to Robert Forrest for Hemingway's sweating waiter and to Julian Barth for his comment on chromhidrosis (you learn something every day). Lipofuscin pigments can be demonstrated in a variety of tissues and conditions - so why do they find their way into the sweat only in certain patients ? I note that Jirka (Lancet 1968, i, 1429) says that his patients showed discolouration of the axillary sweat (apocrine sweat glands) but simultaneously produced colourless sweat from the scapular and lumbar regions (eccrine sweat glands). That must explain why it's the colourless variety that seems to find its way into the lab ! Nick Miller, London [log in to unmask] %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%