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Thiopurine methyltransferase (TPMT) activity is reputed to be an excellent marker for determining patients at risk of azathioprine myelotoxicity. Does anyone know where the activity can be measured and/or the variant alleles determined in the UK? Dr. Eric S. Kilpatrick Consultant in Chemical Pathology Department of Clinical Biochemistry Hull Royal Infirmary Anlaby Road Hull HU3 2JZ Tel 01482-674312 Fax 01482-674310 ______________________________________________________ Get Your Private, Free Email at http://www.hotmail.com %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%