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Could anyone (within easy postal reach of N. Wales!) offer a urine assay for lactulose/mannitol ratio following an oral load, for assessment of intestinal permeability? This is likely to be a one-off request and has arisen following a request by an 'informed' patient to the physician looking after him. Peter Hudson Principal Biochemist Wrexham Maelor Hospital Wales, UK. LL13 7TD [log in to unmask] %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%