>
> I am a biologist, considering whether or not it is correct to carry out a
> Bonferonni procedure on my data, and would be very grateful for any advice.
>
> (details deleted)
>
> Thanks,
>
> Steve Rossiter
We compared (by simulation) a number of corrections for multiplicity, see
Brown, B. W. and Russell, K. "Methods Correcting for Multiple Testing:
Operating Characteristics." Statistics in Medicine, 16: 2511-2528 (1997).
Bonferroni is, of course, very conservative. We like the graphic method
described below as a starting point to seeing what is going on.
Schweder, T. and Spjotvoll, E. "Plots of P-values to evaluate many tests
simultaneously." Biometrika 69: 493-502 (1982)
Code for these methods is available on our web site
http://odin.mdacc.tmc.edu/anonftp/
Barry W. Brown
Department of Biomathematics,
Box 237
University of Texas M. D.
Anderson Cancer Center
1515 Holcombe Blvd
Houston, TX 77030
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