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In message <[log in to unmask]>, andy Stearman <[log in to unmask]> writes > >Formal criteria for the diagnosis of the serotonin syndrome have been >suggested by Sterbach in which coincidental to the use of a known >serotonergic agent at least three of the following must be present > agitation mental status changes > > diaphoresis myoclonus > > diarrhoea fever > > hyperreflexia tremor > > incoordination > Does this sound a bit like Malignant Hyper-pyrexia to anyone? If there's an element of skeletal muscle over-stimulation, might Dantrolene be useful? (readily accessible in any theatre / recovery / ITU, can give iv)