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I haven't seen the study yet, however... I have tried it so far in four patients. The protocol is something like this .... 4% Lignocaine (lidocaine for Americans) by metered dose spray (doesn't acrtually come in one and needs to be either extemporaneously prepared by a pharmacist or via a recycled Rhinocort insufflator bottle) given up to 5 puffs or so to affected (ipsilateral) nostril. Relief is quick but last only 20-30 minutes. As one of my more habitual sufferers (of migraine) stated last week "It didn't work for me, but I do think it has a place ..." I guess for a sufferer of bad migraine even 20 minutes relief would be blissful. I will keep offering it until I get a feel for it. PS: The above patient said she hated Imigran (sumatriptan) as it gave her an awful feeling of "cardiovascular" disturbance ---------- > From: John Sanfey <[log in to unmask]> > To: gp-uk discussion <[log in to unmask]> > Subject: New Migraine Rx - info? > Date: Wednesday, 30 October 1996 10:35 > > Dear all, > A patient gave me a newspaper cutting from a newspaper reporting that > nose drops containing Lidocaine provided rapid and effective pain relief in 55% > of patients with migraine according to a study by Southern California Permanent > Medical Group. Relief occured within 5 minutes. 40% of those who did respond had > a relapse within an hour however. > > Has anyone heard of this interesting study? > > John Sanfey > %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%