 |
 |
I have a new patient with fairly mild but bothersome angio-oedema over the last 18 months, consisting of lip and, to a lesser extent, eye swelling. She has a daughter who has severe urticaria at times. I have sent off bloods for C1 esterase inhibitor levels, IgE etc, but I would be grateful if any of the group have had any experience in dealing with patients like this and could offer advice. She responds well to oral steroids but not at all to terfenadine. I have read that adding Cimetidine or rantidine helps, or that it is worth trying hydroxyline or cyproheptadine hydrochloride.. She is only helped a bit by chlorpheniramine and does not like the sedation. ?Plasmin inhibitors such as alpha-aminocaproic acid danazol etc. I have only just begun subscribing to gp-uk. I am a half-time partner in Horwich, Lancs and the other half of my time is in Ophthalmology, both in the NHS at the Royal Eye Hospital in Manchester and privately doing excimer laser work in the same city with Optimax Laser Eye Clinics. (cf http://www.demon.co.uk/optimax/). Hence, if there are any queries in Ophthalmology or to do with refractive surgery, I would be happy to try and oblige. Stephen Doyle Dr Stephen J Doyle H: 17 Dale View,Chorley,Lancs,PR7 3QJ,UK Tel: 01257-279419 W1: Market Surgery, Horwich, Lancs BL6 5QF Tel: 01204-697696 W2: Manchester Royal Eye Hospital, M13 9WH Tel: 0161-276-5562 W3: Optimax Laser Eye Clinic,Manchester M2 3FU Tel: 0161-839-9369 %%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%