The question is, Kumara

Why would you administer HCQ with or without macrolides to begin with? [Just because there is no effective Rx is not good reason “to try something”. ]

Ben

Sent from my iPad - excuse typos and brevity

On May 25, 2020, at 7:15 PM, Kumara Mendis <[log in to unmask]> wrote:

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Dear all

In Sri Lanka everyone who is admitted to the designated hospitals with PCR+ COVID gets at least Chloroquine /HCQ

The Lancet has published a study

Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis

The findings are :

We were unable to confirm a benefit of hydroxychloroquine or chloroquine, when used alone or with a macrolide, on in-hospital outcomes for COVID-19. Each of these drug regimens was associated with decreased in-hospital survival and an increased frequency of ventricular arrhythmias when used for treatment of COVID-19.

Has anyone done a critical appraisal of this paper?

My question if you are a clinicians would you give HCQ and or macrolide to each and every person (I will add my own criteria after taking an ECG and if there is no abnormal changes of rhythm or other ischaemic changes)

Would much value your comments

Thank you

Kumara

Truth, wisdom, learning, and good sense—these are worth paying for, but too valuable for you to sell.

Proverbs 23:23

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