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Hi Ed,
The international consensus agreed up on a few years ago is to report all faecal Hb results in ug Hb/ g faeces.
Here’s a link to the discussion document by Callum Fraser from the World Endoscopy Organisation FIT expert working group that describes the rationale;
The individual analysers all generate a result in ng/mL that is then converted to ug/g. Because the different analytical FIT systems use different buffer volumes and collect different amounts of faeces on the
collection stick the “ng/mL” result is not comparable between analysers. The ug Hb/ g faeces means that results obtained on different manufacturer systems can be compared.
I hope this makes sense? In short – ug Hb/ g faeces!
Best wishes
Sally
Sally C Benton FRCPath
Consultant Biochemist/ Hub Director,
Clinical Biochemistry, Royal Surrey County Hospital/ NHS Bowel Cancer Screening South of England Hub
Berkshire and Surrey Pathology Services
Joint venture between Ashford & St Peter’s Hospital NHS Foundation Trust, Frimley Health NHS Foundation Trust,
Royal Berkshire NHS Foundation Trust and Royal Surrey Hospital NHS Foundation Trust
Postal address NHS Bowel Cancer Screening Hub, 20 Priestley Road, Surrey Research Park, Guildford
Postcode GU2 7YS
Tel: 01483 409850
PA: Kate Randall
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Email: [log in to unmask]
www.berkshireandsurreypathologyservices.nhs.uk
From: Clinical
biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of
Hinchliffe Edward (R0A) Manchester University NHS FT
Sent: 09 March 2020 17:16
To: [log in to unmask]
Subject: FIT units
Hi,
Apologies if this question has been asked before – there appears to be disagreement on the units for reporting quantitative FIT results. We are currently verifying the MH-JACKarc assay however there seems to be a relatively even proportion
of labs participating in the FIT EQA scheme utilising this method either reporting in ug Hb/g faeces, or ng Hg/mL buffer.
Is there any guidance available (perhaps from the national screening programme) over the preferred units - I would have thought the former (ug Hb/g faeces).
Thanks
Ed
Ed Hinchliffe,
FRCPath
Consultant Clinical Biochemist & Honorary Lecturer
Dept Clinical Biochemistry
Manchester Royal Infirmary
Tel: 0161 701
0578
E-mail:
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