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Dear Kev, you might consider Peter Jüni's paper on flawed analysis in the CLASS trial https://www.bmj.com/content/324/7349/1287 Best Senior Researcher Andreas Lundh, MD, MSc, PhD Centre for Evidence-Based Medicine Odense (CEBMO) Odense University Hospital Kløvervænget 10, 13th Floor, Gate 112 5000 Odense C Denmark Cell: +45 5142 7684 Phone: +45 2479 2553 E-mail: [log in to unmask] *www.cebmo.dk <http://www.cebmo.dk>* Fellow Andreas Lundh, MD, MSc, PhD Department of Infectious Diseases Hvidovre Hospital Kettegård Allé 30 2650 Hvidovre Denmark Cell: +45 5022 5298 Phone: +45 3862 3862 E-mail: [log in to unmask] <[log in to unmask]> [image: CEBMO LOGO] <[log in to unmask]> <[log in to unmask]> <[log in to unmask]> <[log in to unmask]> Den lør. 30. nov. 2019 kl. 10.41 skrev K Hopayian < [log in to unmask]>: > Ta > > iPhone messages often brief not intended brusque > > On 29 Nov 2019, at 14:17, Anoop B <[log in to unmask]> wrote: > > > From what I have seen, adjusting for confounders is one area that needs to > be improved: Either there are number of confounders missing because they > didn't measure or they didn't want to include in i the analysis. I would > like to see a sort of confounder map/cloud that shows the potential > confounders and mediators AND how/why they selected these as confounders. > Then include the confounders that you measured. This way readers could > clearly see which confounders are missing and which were could be measured > in the study. Also, ideally the confounder list should be pre-registered. > > On Thu, Nov 28, 2019 at 12:23 PM K Hopayian < > [log in to unmask]> wrote: > >> Dear Colleagues >> When teaching appraisal of internal validity, it helps to give real >> examples with flaws (biases). It is quite easy to find flawed examples for >> most aspects of a study but when it comes to analysis most examples I have >> are limited: (lack of) Intention to Treat and failure to adjust for >> possible confounders. What is more, they are getting old now. Does anyone >> have examples they could share? >> >> Or does doing so count as “flaw shaming”? ;–) >> >> Kev >> >> Prof. Kev (Kevork) Hopayian, >> BSc, MB BS, MD, FRCGP, DCH, DRCOG >> Clinical Professor, University of Nicosia, Cyprus >> RCGP [INT] Member >> Sessional GP, Suffolk >> >> >> >> >> ------------------------------ >> >> To unsubscribe from the EVIDENCE-BASED-HEALTH list, click the following >> link: >> >> https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=EVIDENCE-BASED-HEALTH&A=1 >> > > ------------------------------ > > To unsubscribe from the EVIDENCE-BASED-HEALTH list, click the following > link: > > https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=EVIDENCE-BASED-HEALTH&A=1 > ######################################################################## To unsubscribe from the EVIDENCE-BASED-HEALTH list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=EVIDENCE-BASED-HEALTH&A=1