Dear Yangmei, Are the first two runs repeated conditions - e.g. is the experiment: Run 1: A1B1 and A1B2 Run 2: A1B1 and A1B2 Run 3: A2B1 and A2B2 Run 4: A2B1 and A2B2 ? Kind Regards Matthew -------------------------------- Dr Matthew Webster FMRIB Centre John Radcliffe Hospital University of Oxford On 6 Nov 2019, at 08:05, Yangmei luo <[log in to unmask]<mailto:[log in to unmask]>> wrote: Dear FSL experts, I have a complicated design so I'd appreciate some help. My experiment is a 2*2 within-subject design. My experiment has 4 runs, and the first two runs included condition A1B1 and A1B2, and the second two runs included condition A2B1 and A2B2. I modeled 2-factor and 2-level on the run level. Given that each level (A1 and A2) has two runs, I would like to model linear habituation between runs for A1 and A2 at the subject level, respectively. How could I set in the GLM design at the subject level? All the best, Yangmei ######################################################################## To unsubscribe from the FSL list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=FSL&A=1 ######################################################################## To unsubscribe from the FSL list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=FSL&A=1