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Hi Xiangyu, Your z-stat file has voxels containing nan, which is causing cluster some problems. You can correct this with fslmaths and the -nan option, but it’s probably worth going back to your original data in case the nans originated there as it may affect any other results generated from that file. Kind Regards Matthew -------------------------------- Dr Matthew Webster FMRIB Centre John Radcliffe Hospital University of Oxford On 29 Oct 2019, at 21:01, Xiangyu Long <[log in to unmask]<mailto:[log in to unmask]>> wrote: Hi FSL community, Recently I performed a correlation analysis with FLAME1 and used easythresh to threshold the outputs as follows: easythresh zstat.nii.gz mask.nii.gz 2.3 0.05 mask.nii.gz zstat_thresh however, the thresholded map still have lots of scattered small clusters all over the brain. I think the smaller clusters should be removed after corrections. Here are the dataset: zstat map: https://www.dropbox.com/s/1rvwhsozuo42on8/zstat.nii.gz?dl=0 mask: https://www.dropbox.com/s/z85h9biigykwkpm/mask.nii.gz?dl=0 Would you please help to check about this? Thanks for your time. Best, Xiangyu ######################################################################## To unsubscribe from the FSL list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=FSL&A=1 ######################################################################## To unsubscribe from the FSL list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=FSL&A=1