Dear Dr. Litvak,Thank you for your reply.I have some masks in native space (.nii) and want to extract source activity in desired regions. It seems that applying the mask in invert step (imaging, custom) restricts the solution space to the regions in mask. Am I true?I want to perform whole brain source localization and extract activity for defined regions . How can I use the masks properly?Any suggestion is appreciated.Best regards,SanaDear Sana,In the 'Inversion results' batch module you can select the 'Output space' option as 'native'.Best,VladimirDear SPM users,Hi,Is there any option in SPM to use 3D source reconstruction (imaging approach) in individuals' space rather than MNI space?I have some masks created in subjects' space, and I want to perform source localization based on these masks.Best regards,Sana