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Dear FSL experts, I want to use “FAST Segmentation” to segment GM/WM/CSF from a skull-stripped 3T T1-weighted MR image. But it classifies all the brain regions as GM. I have tuned the parameters, but it still not work. I used the command like “/usr/local/fsl/bin/fast -t 1 -n 3 -H 0.1 -I 4 -l 20.0 -o $Output_dir $Input_dir ” I have also tested the same command on some other types of 3T T1-weighted MR image, the result seems good. I want to ask: Is there any requirement of the input of T1-weighted MR image? Why it works well on some types of T1-weighted MR image work well, but collapses on other types of T1-weighted images. Could you give me some advice on this? I am looking forward for your feedback. Best regards, Qiong ######################################################################## To unsubscribe from the FSL list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=FSL&A=1