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Hi Lara,

Yes, it is ok.

All the best,

Anderson


On Wed, 22 May 2019 at 14:18, Lara Foland-Ross <[log in to unmask]>
wrote:

> Hi FSL experts,
>
> I running an analysis comparing longitudinal activation differences
> between two groups. All subjects have two timepoints.
>
> In reading up on the listserv and the FEAT webpage (specifically
> https://fsl.fmrib.ox.ac.uk/fsl/fslwiki/GLM#Randomise_details-14), it
> seems that one viable way of approaching this analysis is to calculate
> paired differences within-subjects (computed via fslmaths), then use a
> two-sample t-test to test whether the run1-run2 difference differed between
> the two groups.
>
> Is it appropriate to control for sex and baseline age at the two-sample
> t-test level?
>
> Many thanks,
> Lara
>
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