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Dear Randy,

thank you very much, I had a look at it and it seems that fortunately it
was one of the "straighforward" cases.

Best,

Almudena

El jue., 14 mar. 2019 a las 14:48, Randy Read (<[log in to unmask]>) escribió:

> Dear Almu,
>
> We have a discussion on the Phaser Wiki about some of the possibilities
> for tNCS, what you should look for, and what Phaser can handle:
> http://www.phaser.cimr.cam.ac.uk/index.php/Molecular_Replacement#Translational_Non-crystallographic_Symmetry.
> As it explains, if you have one major peak in the native Patterson then
> everything will be pretty automatic, and it can even be straightforward if
> you have several peaks corresponding to multiples of the same underlying
> translation.  If you have some specific questions about your problem after
> you’ve read that and run Phaser on your problem, then let us know!
>
> Best wishes,
>
> Randy
>
> -----
> Randy J. Read
> Department of Haematology, University of Cambridge
> Cambridge Institute for Medical Research    Tel: +44 1223 336500
> Wellcome Trust/MRC Building                         Fax: +44 1223 336827
> Hills Road
> E-mail: [log in to unmask]
> Cambridge CB2 0XY, U.K.
> www-structmed.cimr.cam.ac.uk
>
> > On 14 Mar 2019, at 05:07, Almudena Ponce Salvatierra <
> [log in to unmask]> wrote:
> >
> > Dear all,
> >
> > I have a dataset with strong TNCS and I would like to know if there are
> a "series of steps" that I could follow in order to find out whether I can
> solve my structure or not.
> >
> > I see on the Phaser wiki that structure determination in the presence of
> TNCS is not fully automated. which steps are those in which my intervention
> should be needed and what do I look for?
> >
> > It is the first time that I deal with this problem and I'd be immensely
> thankful if I could get some hints from those of you who have encountered
> it in the past or understand where in particular I should keep and eye on :)
> >
> > All the best,
> >
> > cheers,
> >
> > Almu
> >
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> >
>
>

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