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Or possibly stabilise at the GP surgery?

Yusuf

Yusuf Gray
Biomedical Scientist Team Manager – Point of Care Technologies
Derbyshire Pathology
University Hospitals of Derby and Burton NHS Foundation Trust
Royal Derby Hospital

Telephone 01332 788537
Mobile 0737 938 0799
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From: Clinical biochemistry discussion list <[log in to unmask]> On Behalf Of Sharpe, Peter
Sent: 01 March 2019 13:31
To: [log in to unmask]
Subject: Re: Pseudohyperkalaemia

We are currently auditing all phoned out K results > 6.5 mmol/l. There are 6-7 every day phoned to primary care and over the last 6 weeks of the audit all were pseudohyperkalaemias – the majority of  patients were sent urgently to A&E.

One has to really wonder about the value of K as part of the GP electrolyte profile – it is certainly causing a lot of harm. Other ways to resolve – better, more regular transport, GP centrifuges, phlebotomy hubs. We remove potassium results from all samples > 24 hours old, and put a warning/disclaimer on all those between 6-24 hours. Perhaps we need to remove all > 6 hours or lower?

Kindest regards
Peter

Dr Peter Sharpe
Consultant Chemical Pathologist
Associate Medical Director, Research & Development
Southern Health & Social Care Trust
Ext: 60869
Tel: 028 38360696
Fax: 028 38334582

From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Misra, Shivani
Sent: 01 March 2019 13:02
To: [log in to unmask]<mailto:[log in to unmask]>
Subject: Re: Pseudohyperkalaemia

Such a difficult issue

A more controversial solution is to de-couple electrolytes from a GP-requested renal function altogether.
Is NA+ and K+ as part of routine renal function in a GP setting adding much value or causing more harm?

In my experience the vast majority of spurious cases occur in people having routine bloods ..…but of course if there was a legitimate reason to request electrolytes then it could be included as a separate request

Shivani

Shivani Misra MRCP, FRCPath, PhD
Consultant in Metabolic Medicine & Diabetes
Imperial College Healthcare NHS Trust

From: Clinical biochemistry discussion list <[log in to unmask]<mailto:[log in to unmask]>> on behalf of "JONES, Stuart (BARKING, HAVERING AND REDBRIDGE UNIVERSITY HOSPITALS NHS TRUST)" <[log in to unmask]<mailto:[log in to unmask]>>
Reply-To: "JONES, Stuart (BARKING, HAVERING AND REDBRIDGE UNIVERSITY HOSPITALS NHS TRUST)" <[log in to unmask]<mailto:[log in to unmask]>>
Date: Friday, 1 March 2019 at 12:55
To: "[log in to unmask]<mailto:[log in to unmask]>" <[log in to unmask]<mailto:[log in to unmask]>>
Subject: Re: Pseudohyperkalaemia

This was becoming a major issue for us too. We were finding that many cases of spurious hyperkalaemia (primarily due to delay between bleed and spin) were not being picked up. We’ve had to have a complete re-think on sample reception logistics and we now stipulate that all primary care ‘critical’ hyperkalaemias have to be reviewed by the on call consultant biochemist before being phoned to out. These can be very difficult decisions to make!

Stuart

From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Mike Addison
Sent: 01 March 2019 12:38
To: [log in to unmask]<mailto:[log in to unmask]>
Subject: Pseudohyperkalaemia

This year alone I have heard of 3 cases of individuals amongst a small cohort of friends  and acquaintances being contacted by their respective GP practices to be told to take themselves urgently to A&E because of high potassium results in blood taken at the GP surgery.  In the past this also happened to my wife.  The anxiety and disruption caused to these patients whose repeat potassium results were normal was considerable.  The cost implication to the NHS  is also a factor as in A&E many more tests, other than potassium, were carried out and patients were in A&E for a considerable period of time.

I have been too long retired to have kept up to date in this field but someone must have done audits of hyperkalaemia in samples from GP practice and the prevalence of true versus pseudohyperkalaemia in them.  Do GPs check for known causes of pseudohyperkalaemia before rushing the patient off to hospital?  Are there guidelines for this?  And is this such a problem that GP should have POCT in the surgery?

Are you all prepared for Brexit?

Dr Mike Addison


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