Hi everyone,

I want to statistically analyze two groups (ie. Alzheimer's and healthy controls) of resting state functional maps (output using ICA) using a t-test. 
I thought to use FEAT in order to accomplish this, however, it seems like in order to do so I must enter a design (such as a block design).  This isn't the case for resting state.   

I've come across this: https://fsl.fmrib.ox.ac.uk/fsl/fslwiki/GLM
But it doesn't discuss what to do in the case of resting state.

Would anyone happen to have any advice or even a reference to something I can look at?

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