It is surprising that you have a TR=2s with multi-band data.  What kind of data is this?v  That will be important to answer all these questions.  

Matt.

From: FSL - FMRIB's Software Library <[log in to unmask]> on behalf of "Wu, Junjie" <[log in to unmask]>
Reply-To: FSL - FMRIB's Software Library <[log in to unmask]>
Date: Thursday, February 14, 2019 at 3:56 PM
To: "[log in to unmask]" <[log in to unmask]>
Subject: [FSL] Slice timing correction and FIX

Dear FSL community,

I am using MELODIC to process multiband resting state fMRI data. I have questions on slice timing correction and FIX.

1) Should slice timing correction be used for resting state data of TR = ~ 2s? Slice timing correction is not included in Human Connectome Project pipeline. However, HCP data would not be affected much by slice timing effects because TR of the HCP data is relatively short (720ms) as compared to TR of conventional fMRI data (about 1.5s - 3s).

2) If slice timing correction is not strongly unrecommended, how to perform slice timing correction for multiband data?

3) Is it appropriate to use trained-weights files supplied with FIX to remove noise components in an fMRI dataset, where the acquisition and preprocessing parameters are close to one of the example training-input data? In this case, how well dose FIX perform?

Thanks,

Junjie

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