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Dear Wolfram, For the past several years, Rigaku has been installing only HPC (Hybrid Photon Counting) X-ray area detector -based diffractometer systems: in conjunction with microfocus rotating anode, microfocus sealed-tube and other X-ray sources. (Most recently, we have been deploying the Rigaku HyPix-6000HE HPC detector.) The advantages of the HPC technology over any of the phosphor-based detector types (CCD, CMOS and CPAD, etc…) are notable: most particularly the discrete each-and-every single photon counting capability, extremely high dynamic range, small pixel size and the single pixel point function and very rapid read-out. With these advantages, significantly higher resolution data can be achieved, - and more speedily, compared to the other detector types. (We have a number of established ‘application note’ examples.) In order to prove the advantages for your purposes, the best might be to collect data from a range of your own crystal samples. – There is an open invitation for any seriously interested groups to collect data from their crystals in our applications labs. Please contact your local good Rigaku salesperson. Many Thanks, Yours sincerely, Marcus Winter Rigaku. From: CCP4 bulletin board [mailto:[log in to unmask]] On Behalf Of wtempel Sent: Tuesday, January 15, 2019 6:20 PM To: [log in to unmask] Subject: [ccp4bb] hybrid photon counter in the home lab Hi, I would value your opinions in this equipment-related question. Allé et al have compared detector types with a molybdemon source for a small molecule application<https://dx.doi.org/10.1088/0031-8949/91/6/063001>. Are there similar published comparisons for protein crystallography? What benefits can I expect from replacing a CCD detector with a hybrid photon counter at an energy of 8 keV and in the absence of the flux that a modern synchrotron provides? Thank you in advance. Wolfram Tempel ________________________________ To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1