| How will you make the most of your “freed-up February” thanks to those revised NHMRC grant deadlines? Why not by joining your clinician-researcher peers and eminent experts for one or more of these ACTA Summer School workshops? If you already aware of Summer School and intent on attending, a word to the wise: These workshops will fill up. And now’s a really good time to register by clicking on the above links and taking advantage of short-term availability of early-bird pricing.
If you’ve not heard news of ACTA Summer School, read on. ACTA is about growing, strengthening and supporting the clinical trials and registries sector to deliver Better health through best evidence. And Summer School is about equipping you with tools, techniques and inspiration to play big part in that.
Some Summer School workshops cover general clinical trials and registry capacity building, while others are gratifyingly geeky, BYO-laptop, conundrums and calculations “clinics” or “hackathons”. They all are led by inspirational experts drawn from the ACTA community and internationally further afield. Below is the full list of Summer School Workshops linked directly to registration. Scroll down for further details of each. After that, please pass-on this email to colleagues and peers who may be new to or unaware of ACTA. |
| Registry-randomised Trials Workshop | Hear from trialists who have successfully run trials utilising clinical quality registries as well as policy makers and funders. Delegates will have the opportunity to engage with speakers and be equipped to utilise these methodologies. The goal is to leave with a clear pathway as to how registries can be engaged in making trials better, cheaper, easier, and quicker. When? Mon 11 February 2019, 8:30 am – 5:30 pm Where? SAHMRI (South Australian Health and Medical Research Institute), North Terrace, Adelaide, SA 5000 Register |
| Innovative Trial Design Clinic | Curious as to how to apply adaptive trial methodologies that might benefit your research question?
We invite you to present your current research question to a panel who will engage with the audience to provide expert guidance on how you could avoid many of the design decisions you might otherwise regret (like having the wrong sample size calculation, or ‘type III error’ of having chosen the wrong intervention). Don’t have a question in mind but keen to learn from what others are doing? Join the audience.
Presenters will receive complimentary registration to the event. Email [log in to unmask].au to express your interest in presenting.
When: Fri 15 February 2019, 8:30 am – 5:00 pm
Where: The George Institute for Global Health, 1 King Street, Level 5, Newtown, NSW 2042
Register |
| Adaptive clinical trial designs: theory and hands-on skills development – Melbourne | Join us for a two-day intensive workshop where you will take away the knowledge and practical skills that are fundamental for designing adaptive clinical trials. You will get hands-on experience in applying cutting edge methods and numerical simulations using R and/or STATA.
We are thrilled to welcome expert presenters from the University of Cambridge: James Wason, Adrian Mander, David Robertson and Newcastle University (UK) Michael Grayling.
This event is part of the Victorian Centre for Biostatistics (ViCBiostat) Summer School. Find out more about the full ViCBiostat summer School program (18-22 Feb) here. Members of ViCBiostat are eligible for discounts on this course- select "ACTA Member/ViCBiostat" when purchasing your ticket.
Clinical trials are the gold standard study design for assessing the efficacy and safety of an intervention. Adaptive designs are a novel approach to improving the efficiency and ethical properties of clinical trials. With an adaptive design, information gathered during the trial can be used to change the design in a statistically robust way. There are many types of adaptive designs that are possible for different situations ranging from phase I to phase III.
In both adaptive and non-adaptive trials, there are often multiple hypotheses being tested. Examples include trials with multiple endpoints, multiple treatment arms and when a trial tests a treatment in different patient subgroups. Adaptive trials often mean that a particular hypothesis is tested several times during the trial. This creates issues with multiple testing, for which suitable procedures are needed to ensure the appropriate error rate is controlled.
In this course we will give an overview of multiple testing issues and adaptive designs in trials. Participants will learn about a variety of new adaptive clinical trial designs, including multi-arm multi-stage (MAMS), umbrella studies and adaptive randomisation. As well as learning about how to design adaptive trials we will cover the implications of the design on the analysis and practical aspects of running the trial.
Throughout the course, real examples will be used to demonstrate the methodology. There will be a strong emphasis on learning how to use available software (in both R and Stata depending on the preference of the delegate) to implement the methodology in practice. The course is aimed at statisticians, although non-statisticians with strong quantitative experience would benefit from the course also.
Experience in STATA and/or R is required, as is a laptop with the software loaded for the course.
When?
Thu 21 February 2019, 8:45 am – Fri 22 February 2019, 5:00 pm
Where?
The Royal Children's Hospital
50 Flemington Road
HELP Centre, Level 1, Room 1.046a and 1.046b
Parkville, VIC 3052
View Map
Register |
| Adaptive clinical trial designs: theory and hands-on skills development – Brisbane | Join us for a two-day intensive workshop where you will take away the knowledge and practical skills that are fundamental for designing adaptive clinical trials. You will get hands-on experience in applying cutting edge methods and numerical simulations using R and/or STATA
We are thrilled to welcome expert presenters from the University of Cambridge: James Wason, Adrian Mander, David Robertson and Newcastle University Michael Grayling
Clinical trials are the gold standard study design for assessing the efficacy and safety of an intervention. Adaptive designs are a novel approach to improving the efficiency and ethical properties of clinical trials. With an adaptive design, information gathered during the trial can be used to change the design in a statistically robust way. There are many types of adaptive designs that are possible for different situations ranging from phase I to phase III.
In both adaptive and non-adaptive trials, there are often multiple hypotheses being tested. Examples include trials with multiple endpoints, multiple treatment arms and when a trial tests a treatment in different patient subgroups. Adaptive trials often mean that a particular hypothesis is tested several times during the trial. This creates issues with multiple testing, for which suitable procedures are needed to ensure the appropriate error rate is controlled.
In this course we will give an overview of multiple testing issues and adaptive designs in trials. Participants will learn about a variety of new adaptive clinical trial designs, including multi-arm multi-stage (MAMS), umbrella studies and adaptive randomisation. As well as learning about how to design adaptive trials we will cover the implications of the design on the analysis and practical aspects of running the trial.
Throughout the course, real examples will be used to demonstrate the methodology. There will be a strong emphasis on learning how to use available software (in both R and Stata depending on the preference of the delegate) to implement the methodology in practice. The course is aimed at statisticians, although non-statisticians with strong quantitative experience would benefit from the course also.
Experience in STATA and/or R is required, as is a laptop with the software loaded for the course.
When? Mon 25 February 2019, 8:45 am – Tue 26 February 2019, 5:00 pm
Where? Location TBC
Register |
| Adaptive Clinical Trial Designs: theory and hands-on skill development – Sydney | Join us for a two-day intensive workshop where you will take away the knowledge and practical skills that are fundamental for designing adaptive clinical trials. You will get hands-on experience in applying cutting edge methods and numerical simulations using R and/or STATA
We are thrilled to welcome expert presenters from the University of Cambridge: James Wason, Adrian Mander, David Robertson and Newcastle University Michael Grayling
Clinical trials are the gold standard study design for assessing the efficacy and safety of an intervention. Adaptive designs are a novel approach to improving the efficiency and ethical properties of clinical trials. With an adaptive design, information gathered during the trial can be used to change the design in a statistically robust way. There are many types of adaptive designs that are possible for different situations ranging from phase I to phase III. In both adaptive and non-adaptive trials, there are often multiple hypotheses being tested. Examples include trials with multiple endpoints, multiple treatment arms and when a trial tests a treatment in different patient subgroups. Adaptive trials often mean that a particular hypothesis is tested several times during the trial. This creates issues with multiple testing, for which suitable procedures are needed to ensure the appropriate error rate is controlled. In this course we will give an overview of multiple testing issues and adaptive designs in trials. Participants will learn about a variety of new adaptive clinical trial designs, including multi-arm multi-stage (MAMS), umbrella studies and adaptive randomisation. As well as learning about how to design adaptive trials we will cover the implications of the design on the analysis and practical aspects of running the trial. Throughout the course, real examples will be used to demonstrate the methodology. There will be a strong emphasis on learning how to use available software (in both R and Stata depending on the preference of the delegate) to implement the methodology in practice. The course is aimed at statisticians, although non-statisticians with strong quantitative experience would benefit from the course also. Experience in STATA and/or R is required, as is a laptop with the software loaded for the course. When? 28 February 2019, 8:45 am – Fri 1 March 2019, 5:00 pm
Where? Sydney, location The George Institute Register |
| ACTA gratefully acknowledges operational funding from the Australian Government's Medical Research Future Fund |
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