If you want to do a FEAT analysis with ASL the best advice is to follow the suggestions here: https://fsl.fmrib.ox.ac.uk/fsl/fslwiki/FEAT/UserGuide#Perfusion_FMRI_Analysis
You can do something very similar to BOLD, but you don't do all of the pre-processing and it is generally reasonable to not apply a HRF.

Michael

On 28 Nov 2018, at 16:52, Vasile, Eduard <[log in to unmask]> wrote:

Dear all, 
 
I have a question about ASL fMRI data analysis. I run a series of scans using pcASL but I am not interested in perfusion quantification. I simply wish to see if there are any activation differences between the EVs. I did a subtraction via asl_file and now I am trying to use FEAT to do an EVs analysis. I am wondering if the subtracted data needs any other processing before FEAT and if FEAT can be run as with BOLD data and EVs.
 
Thank you!
 
Kind regards
Eduard 

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Michael Chappell MEng DPhil
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Associate Professor, Institute of Biomedical Engineering, University of Oxford.
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