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Thanks Manuel, It is the same thing that I understood. But I did not expect to have big differences when I fitted the same DTI data by using two different procedures, with --kurt and without --kurt. FA difference between, for example, 0.72 and 0.42 in the same voxel, is big. Maurizio > Hi Maurizio, > > If I understand correctly, when you activate the --kurt option, you are fitting the kurtosis model, that is more suitable for multishell data. The >problem is if you want to compare with other FA values from literature, then probably you'd like to split the data and just use dtifit to one shell >without the --kurt flag. I hope this helps. > >Best regards, > >Manuel >>Hello, >>It is the first time that I use a DTI multishell acquisition. My question is related to dtifit. >>When I use dtifit, do I have to use the option --kurt to fit my data? >>Because, I used dtifit with and without that option, and I had big differences in FA maps. >>For example, in the same voxel, I had FA=0.72 (without --kurt) and FA=0.42 (with --kurt). >>Thanks, >>Maurizio ######################################################################## To unsubscribe from the FSL list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=FSL&A=1