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Dear FSL experts, Suppose I have two groups (3 subjects in each group), and a voxel-wise regressor (gray matter probability map), and I want to compare group difference after regressing out the gray matter effects. I searched the mail-list, and found the solution (https://www.jiscmail.ac.uk/cgi-bin/webadmin?A2=ind1503&L=fsl&P=R94997&1=fsl&9=A&I=-3&J=on&d=No+Match%3BMatch%3BMatches&z=4) by setting the design matrix like this: 1 0 1 1 0 1 1 0 1 0 1 1 0 1 1 0 1 1 the third column would represent the voxel-wise regressor. However, when I use the Glm GUI to make the design matrix, by setting the "voxel-dependent EVs" to 1, the resulted design matrix would be different to the third column above. Specifically, the third column seems to be random numbers. Thanks in advance. Best, Yang Hu ######################################################################## To unsubscribe from the FSL list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=FSL&A=1