Dear SPM experts, We are trying to obtain the value of the Normalised Mutual Information(nmi) between two images and we have not achieved it yet. We've found a script in the forum which was coded to do so but we have found some differences between it and the spm_coreg function and we don't know which to use since they give us different outputs. cg_hist2d_img.m - Script from the forum H = H/(sum(H(:))+eps); s1 = sum(Hmi,1); s2 = sum(Hmi,2); H = H.*log2((H+eps)./(s2*s1+eps)); mi = sum(H(:)); spm_coreg H = H+eps; sh = sum(H(:)); H = H/sh; s1 = sum(H,1); s2 = sum(H,2); H = H.*log2(H./(s2*s1)); mi = sum(H(:)); nmi = (sum(s1.*log2(s1))+sum(s2.*log2(s2)))/sum(sum(H.*log2(H))); When we apply it using as input the same image twice, we get a value above 1, while we believe it should be 1 (or 0.998). Are the values of NMI supposed to be between 0 and 1? Any insight given will be gratefull Thanks Aran