Hi, This is a question that relates to your specific study and the existing literature in your field, so unfortunately I am not able to advice you on which hypothesis is more likely to be true. Cheers, Janine On 19 Oct 2018, at 08:53, Carlotta Fabris <[log in to unmask]<mailto:[log in to unmask]>> wrote: Yes exactly and because of this I just wanted to know if there is maybe a way to understand which of the different hypothesis we tested with these contrasts is more likely to be true. I hope I explained myself and thank you Janine as always! Il Ven 19 Ott 2018, 09:51 Janine Bijsterbosch <[log in to unmask]<mailto:[log in to unmask]>> ha scritto: Hi, It is important to understand that each different contrast fundamentally asks a different question, so you would not expect to see the same results. The contrasts should be set based on the hypotheses that you want to test in your study, and not based on looking at the results! Best wishes, Janine On 19 Oct 2018, at 08:40, Carlotta Fabris <[log in to unmask]<mailto:[log in to unmask]>> wrote: I tried three different contrasts: [1 -1 1 -1] [1 1 -1 -1] [ 1 -1 -1 1] for all the 6 runs for subject 1 and 2 just to see if I could exclude one of these, but I got very different results and I can't decide which to take out and which not. Is it normal? Should I do every first level analysis including the three contrasts? Thank you, Carlotta. ######################################################################## To unsubscribe from the FSL list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=FSL&A=1 ----- Dr Janine Bijsterbosch Postdoctoral Researcher FMRIB Centre, University of Oxford John Radcliffe Hospital Oxford, United Kingdom [log in to unmask]<mailto:[log in to unmask]> ________________________________ To unsubscribe from the FSL list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=FSL&A=1 ________________________________ To unsubscribe from the FSL list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=FSL&A=1 ----- Dr Janine Bijsterbosch Postdoctoral Researcher FMRIB Centre, University of Oxford John Radcliffe Hospital Oxford, United Kingdom [log in to unmask]<mailto:[log in to unmask]> ######################################################################## To unsubscribe from the FSL list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=FSL&A=1