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Dear FSL experts, I have run Feat with Melodic component analysis on a task-based fMRI paradigm. I used rules defined in previous publication to define noise (doi:10.1016/j.jneumeth.2010.03.028). I only removed components that seemed to be 100% noise thus leaving all components that I suspected partly could be related to any neural signal. It has been discussed in our group whether this denoiseing method can/should be used in a task-based paradigm. The task in the paradigm is simply to look at images displayed on a screen. Contrasting painful images with not painful images which are separated by a fixation cross. What is your view on this? Olof ######################################################################## To unsubscribe from the FSL list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=FSL&A=1