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Hi Carlotta, There is a lot of material in the slides and practicals of the FSL course. In short, you'd have a primary hypothesis at the lower level, e.g., that when the subject does something the BOLD response is higher than the baseline when such activity is not being performed. The contrasts at the lowest level refer to that primary, subject-level, hypothesis. These contrasts will yield effects (COPEs), which can then be tested at the subject level, for example, if responses are stronger in patients than controls or are associated with some continuous, between-subject variable. How to construct depends on your experiment... All the best, Anderson On Thu, 11 Oct 2018 at 03:27, Carlotta Fabris <[log in to unmask]> wrote: > Thank you Anderson! > > I understood what you told me for points 1 and 3, but I have another > question about point 2. > > You wrote: You'll need COPEs to be able to pass results upwards, so yes, > need contrasts, even if your primary hypothesis is all about the higher > level, between-subjects. > What contrasts should I include? How can I decide which one to use and how > to build them? > > Thank you again, > Carlotta. > > ######################################################################## > > To unsubscribe from the FSL list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=FSL&A=1 > ######################################################################## To unsubscribe from the FSL list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=FSL&A=1