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Hi Flora, by looking at the native_space/pvcorr/perfusion_calib.nii.gz I also find high perfusion values in the white matter region and also in the gray matter region (but note, native_space/pvcorr/perfusion_calib.nii.gz is just the partial volume estimation of gray matter map! according to the documentation: https://asl-docs.readthedocs.io/en/latest/oxasl_userguide.html "[...] in this directory [(pvcorr)] the perfusion.nii.gz image is for grey matter, perfusion_wm.nii.gz contains white matter estimates."). I would say that native_space/pvcorr/perfusion_calib.nii.gz image in total is brighter, but also there are a lot of outliers. By looking at the histogram, the mode is 73 ml/100g/min. The range of the histogram ist between 0 and 450. 11% of all CBF voxels >0 are above 150 ml/100g/min, which are spatially equally distributed in the gray matter. Is this normal in pvc maps?? The image native_pace/pvcorr/perfusion_wm_calib.nii.gz is between 0 and 30. There are some local areas wehre the CBF values are between 40 to 90. So far I did not make any analysis on other patients, but I am going to do this in this week. I am going to tell you about the results of the PVC. Regards, Rune ######################################################################## To unsubscribe from the FSL list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=FSL&A=1