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Dear all, A half-day research symposium on Mendelian randomization methodology will take place in Cambridge at the MRC Biostatistics Unit in Cambridge on the morning of Wednesday 21th November 2018. Speakers will be Toby Johnson (GSK), Verena Zuber (Imperial), Frank Dudbridge (University of Leicester), Chris Foley (Cambridge), and Stephen Burgess (Cambridge). Overview: The symposium will take place after the two-day Mendelian randomization course held at the MRC Biostatistics Unit in Cambridge on Monday 19th November and Tuesday 20th November 2018. The symposium is open to both course and non-course attendees. The timetable is as follows: 9.00 Registration 9.30 Session 1: Chris Foley, "Fast and efficient co-localization for simultaneous assessment of shared genetic risk factors across numerous traits genome-wide" 10.10 Session 2: Toby Johnson (GSK), "Insights from finemapping and colocalization analyses for every disease-transcript-tissue triplet" 10.50 Tea 11.10 Session 3: Frank Dudbridge (University of Leicester), "Adjustment for index event bias in genome-wide association studies of subsequent events" 11.40 Session 4: Verena Zuber, "Selecting causal risk factors from high-throughput experiments using multivariable Mendelian randomization" 12.10 Session 5: Stephen Burgess "Valid causal inferences with many invalid instrumental variables via contamination mixture modelling" 12.40 Discussion 13.00 Lunch and finish Please note that registration for the two-day course is still open and places on the symposium can be included as part of registration for the full course at https://onlinesales.admin.cam.ac.uk/conferences-and-events/mrc-biostatistics-unit/mrc-biostatistics-unit-short-courses/mendelian-randomization-course-19-20-november-2018. Registration for the symposium only is at: https://onlinesales.admin.cam.ac.uk/conferences-and-events/mrc-biostatistics-unit/mrc-biostatistics-unit-short-courses/research-symposium-on-mendelian-randomization-methodology-21-november-2018. We hope to see you either on the two-day course or the half-day symposium! Best wishes, Stephen Burgess You may leave the list at any time by sending the command SIGNOFF allstat to [log in to unmask], leaving the subject line blank.